DegronMD - Q86XA9(HEATR5A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F25I	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	FIFEWLRYL	DEG_MDM2_SWIB_1	25:33	Mutation altering degron motif	0.7415
p.F25I	ACH-000980	Lung Cancer	CCLE	FIFEWLRYL	DEG_MDM2_SWIB_1	25:33	Mutation altering degron motif	0.7415
p.F25I	NCI-H1155	lung	COSMIC	FIFEWLRYL	DEG_MDM2_SWIB_1	25:33	Mutation altering degron motif	0.7415

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons