DegronMD - Q86XI2(NCAPG2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S612L	TCGA-60-2720	LUSC	TCGA	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.1111
p.S612L	DO26587	LUSC	ICGC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.1111
p.T610I	TCGA-DU-6392	LGG	TCGA	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.1667
p.T610I	DO22237	LGG	ICGC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.1667
p.P590L	TCGA-FS-A1Z3	SKCM	TCGA	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.P590L	DO37635	SKCM	ICGC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.E600Q	SIDM01265	Plasma Cell Myeloma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation altering degron motif	0.5633
p.E600Q	SIDM00442	Thyroid Gland Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation altering degron motif	0.5633
p.E600Q	SIDM00309	Mesothelioma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation altering degron motif	0.5633
p.N614D	SIDM00633	Breast Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.N614D	SIDM00849	Kidney Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.N614D	SIDM00116	Non-Small Cell Lung Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.N614D	SIDM00954	Breast Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.0556
p.G598R	SIDM00171	Colorectal Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.2778
p.G598R	ACH-000412	Colon/Colorectal Cancer	CCLE	EKENV	DEG_APCC_KENBOX_2	600:604	Mutation rewiring degron network	0.2778

Kaplan plot for NCAPG2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NCAPG2

UniProt ID: Q86XI2

Entrez ID: 54892

Protein name: Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NCAPG2 in