DegronMD - Q86YH2(ZNF280B)

ZNF280B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N280S	TCGA-BR-8680	STAD	TCGA	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation altering degron motif	0.7069
p.N280S	DO47769	STAD	ICGC	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation altering degron motif	0.7069
p.P281L	TCGA-DD-AAVX	LIHC	TCGA	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation altering degron motif	0.6471
p.P281L	DO52283	LIHC	ICGC	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation altering degron motif	0.6471
p.G291R	TCGA-XY-A8S2	TGCT	TCGA	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation rewiring degron network	0.0556
p.D275E	SIDM01624	Bladder Carcinoma	GDSC	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation rewiring degron network	0.2778
p.D275E	SIDM01529	Bladder Carcinoma	GDSC	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation rewiring degron network	0.2778
p.D275E	ACH-000011	Bladder Cancer	CCLE	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation rewiring degron network	0.2778
p.D275E	ACH-000026	Bladder Cancer	CCLE	KKENP	DEG_APCC_KENBOX_2	277:281	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc