DegronMD - Q86Z23(C1QL4)

C1QL4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D238N	TCGA-13-2057	OV	TCGA	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.6932
p.D238N	DO31320	OV	ICGC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.6932
p.K226N	TCGA-44-6778	LUAD	TCGA	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation blocking ubiquitination signal	0.5833
p.K226N	DO25603	LUAD	ICGC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation blocking ubiquitination signal	0.5833
p.T224N	DO229006	LICA	ICGC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation rewiring degron network	0.0833
p.S228I	DO229213	THCA	ICGC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation rewiring degron network	0.1944
p.Y236C	SIDM01113	Other Sarcomas	GDSC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.7087
p.Y236C	ACH-000939	Sarcoma	CCLE	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.7087
p.Y236C	SK-UT-1	soft tissue	COSMIC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.7087
p.Y236S	NCI-H1563	lung	COSMIC	FIIYPD	LIG_APCC_ABBA_1	233:238	Mutation altering degron motif	0.712

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*NOTE: the Kaplan plots were collected from OncoLnc