DegronMD - Q8IUI8(CRLF3)

CRLF3

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GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R248T	TCGA-60-2698	LUSC	TCGA	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation rewiring degron network	0.1111
p.V243I	TCGA-D1-A103	UCEC	TCGA	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation rewiring degron network	0.25
p.F234L	TCGA-DD-AADK	LIHC	TCGA	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation rewiring degron network	0.3056
p.H238L	TCGA-SX-A7SR	KIRP	TCGA	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation altering degron motif	0.7313
p.L230V	DO44242	BRCA	ICGC	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation rewiring degron network	0.1944
p.V228L	SIDM00985	Burkitt's Lymphoma	GDSC	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation rewiring degron network	0.1389
p.V236I	SIDM00971	Breast Carcinoma	GDSC	IVLHID	LIG_APCC_ABBA_1	235:240	Mutation altering degron motif	0.5965

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*NOTE: the Kaplan plots were collected from OncoLnc