DegronMD - Q8IUR5(TMTC1)

TMTC1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H14Q	DO225028	BRCA	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111
p.N2T	DO3001	BRCA	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.7055
p.P3L	DO44907	LIHC	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.7582
p.R14S	DO224563	LUSC	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111
p.N2S	DO42280	UCEC	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.7069
p.L13V	DO42793	UCEC	ICGC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1389
p.C15Y	KP-1N	pancreas	COSMIC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.0833
p.I11T	J82	urinary tract	COSMIC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1944
p.H14R	SNU-1040	large intestine	COSMIC	VVTTS	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc