DegronMD - Q8IV08(PLD3)

PLD3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P168R	TCGA-2Y-A9H1	LIHC	TCGA	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation rewiring degron network	0.25
p.P168R	DO219521	LIHC	ICGC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation rewiring degron network	0.25
p.R162C	TCGA-DC-6154	READ	TCGA	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation altering degron motif	0.719
p.R162C	DO227569	PBCA	ICGC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation altering degron motif	0.719
p.R162C	DO36523	READ	ICGC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation altering degron motif	0.719
p.R162C	SIDM01313	Colorectal Carcinoma	GDSC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation altering degron motif	0.719
p.Q150H	DO228986	LICA	ICGC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation rewiring degron network	0.2222
p.Q150H	DO229045	LICA	ICGC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation rewiring degron network	0.2222
p.G144A	SIDM00545	Melanoma	GDSC	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation rewiring degron network	0.0556
p.R162H	ACH-001707	Leukemia	CCLE	LAPKGVNVRIAV	DEG_ODPH_VHL_1	154:165	Mutation altering degron motif	0.7133

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*NOTE: the Kaplan plots were collected from OncoLnc