DegronMD - Q8IV45(UNC5CL)

UNC5CL

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N62K	TCGA-14-1795	GBM	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.3056
p.N62K	DO13114	GBM	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.3056
p.R66M	TCGA-AP-A051	UCEC	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.R66M	DO42673	UCEC	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.E51K	TCGA-D3-A51G	SKCM	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.E51K	TCGA-EE-A2GU	SKCM	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.E51K	DO37639	SKCM	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.E51K	DO47700	SKCM	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.1944
p.V53M	TCGA-IB-7651	PAAD	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.25
p.V53M	DO46657	PAAD	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.25
p.T57P	TCGA-OR-A5K9	ACC	TCGA	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation altering degron motif	0.7031
p.P70T	DO229034	LICA	ICGC	PTPQLE	DEG_SCF_FBW7_2	56:61	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc