DegronMD - Q8IV56(PRR15)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W13R	TCGA-44-6776	LUAD	TCGA	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation rewiring degron network	0.2222
p.W13R	DO24060	LUAD	ICGC	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation rewiring degron network	0.2222
p.D6E	DO223036	ESCA	ICGC	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation altering degron motif	0.5647
p.W13C	DO44919	LIHC	ICGC	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation rewiring degron network	0.2222
p.G5S	DO38404	STAD	ICGC	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation altering degron motif	0.6993
p.S4G	ACH-001061	Colon/Colorectal Cancer	CCLE	DSGDAGS	DEG_SCF_TRCP1_1	3:9	Mutation altering degron motif	0.8104

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons