DegronMD - Q8IVW4(CDKL3)

CDKL3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T413A	TCGA-56-8305	LUSC	TCGA	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.1944
p.P411L	TCGA-90-A4ED	LUSC	TCGA	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.1389
p.N410H	TCGA-BH-A18J	BRCA	TCGA	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.1111
p.G417C	TCGA-D7-A6EY	STAD	TCGA	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.3056
p.L418F	TCGA-F4-6856	COAD	TCGA	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation altering degron motif	0.587
p.L415V	DO42961	UCEC	ICGC	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.25
p.L415V	DO41349	UCEC	ICGC	LKENP	DEG_APCC_KENBOX_2	418:422	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc