DegronMD - Q8IVW6(ARID3B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G85V	TCGA-68-A59J	LUSC	TCGA	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.0556
p.G85V	DO49085	LUSC	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.0556
p.P65H	TCGA-80-5608	LUAD	TCGA	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.2778
p.P65H	DO23693	LUAD	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.2778
p.T544I	TCGA-DF-A2KN	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.1111
p.T544I	DO223282	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.1111
p.E83Q	TCGA-E7-A7XN	BLCA	TCGA	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.1111
p.E83Q	DO51878	BLCA	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.1111
p.E83Q	DO220823	BRCA	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.1111
p.P68S	TCGA-ER-A19G	SKCM	TCGA	GPLARVPPT	DEG_SIAH_1	67:75	Mutation altering degron motif	0.6752
p.P68S	DO47284	SKCM	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation altering degron motif	0.6752
p.R71S	TCGA-EY-A215	UCEC	TCGA	GPLARVPPT	DEG_SIAH_1	67:75	Mutation altering degron motif	0.6316
p.R71S	DO42665	UCEC	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation altering degron motif	0.6316
p.S545L	TCGA-JW-A5VL	CESC	TCGA	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.0833
p.S545L	DO49976	CESC	ICGC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.0833
p.S545L	DO233873	GACA	ICGC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.0833
p.A523V	DO222762	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.0833
p.S534C	DO228348	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation altering degron motif	0.7541
p.G67C	DO229015	LICA	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation altering degron motif	0.6489
p.A76T	DO228138	PBCA	ICGC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.3056
p.A77T	SIDM00534	Colorectal Carcinoma	GDSC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.2778
p.A77T	ACH-000986	Colon/Colorectal Cancer	CCLE	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.2778
p.A77T	HT-115	large intestine	COSMIC	GPLARVPPT	DEG_SIAH_1	67:75	Mutation rewiring degron network	0.2778
p.Q526R	SIDM00780	Colorectal Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.1667
p.Q525R	ACH-000967	Colon/Colorectal Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	532:536	Mutation rewiring degron network	0.1389

Kaplan plot for ARID3B in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ARID3B

UniProt ID: Q8IVW6

Entrez ID: 10620

Protein name: AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B) (Bright and dead ringer protein) (Bright-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ARID3B in