DegronMD - Q8IX07(ZFPM1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A502T	DO224645	COCA	ICGC	PTPGSS	DEG_SCF_FBW7_1	507:512	Mutation rewiring degron network	0.1944
p.G522R	DO234404	ESAD	ICGC	PTPGSS	DEG_SCF_FBW7_1	507:512	Mutation rewiring degron network	0.0556
p.V957I	DO233267	GACA	ICGC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.1944
p.A939T	DO229032	LICA	ICGC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.0556
p.G510D	DO23440	LINC	ICGC	PTPGSS	DEG_SCF_FBW7_1	507:512	Mutation altering degron motif	0.6087
p.V957L	DO34128	PACA	ICGC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.1944
p.S953T	DO229211	THCA	ICGC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.3056
p.P946L	DO229211	THCA	ICGC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.25
p.P950A	SIDM00537	Colorectal Carcinoma	GDSC	PPSY	ITCH	949:952	Mutation altering degron motif	0.7503
p.P950A	ACH-000982	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	949:952	Mutation altering degron motif	0.7503
p.P950A	ACH-001345	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	949:952	Mutation altering degron motif	0.7503
p.P950A	GP5d	large intestine	COSMIC	PPSY	ITCH	949:952	Mutation altering degron motif	0.7503
p.A939V	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.0556
p.T959A	ACH-000982	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	949:952	Mutation rewiring degron network	0.1389
p.T959A	ACH-001345	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	949:952	Mutation rewiring degron network	0.1389
p.T959A	GP5d	large intestine	COSMIC	PPSY	ITCH	949:952	Mutation rewiring degron network	0.1389
p.R499G	ACH-001289	Rhabdoid	CCLE	PTPGSS	DEG_SCF_FBW7_1	507:512	Mutation rewiring degron network	0.1111

Kaplan plot for ZFPM1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZFPM1

UniProt ID: Q8IX07

Entrez ID: 161882

Protein name: Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZFPM1 in