DegronMD - Q8IXI1(RHOT2)

RHOT2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P48Q	TCGA-CX-7219	HNSC	TCGA	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation altering degron motif	0.7035
p.P48Q	DO14910	HNSC	ICGC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation altering degron motif	0.7035
p.P52H	TCGA-EE-A17Y	SKCM	TCGA	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2778
p.P52H	DO47459	SKCM	ICGC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2778
p.E39D	TCGA-IB-7651	PAAD	TCGA	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2222
p.E39D	DO46657	PAAD	ICGC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2222
p.A44E	SIDM00241	Breast Carcinoma	GDSC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation altering degron motif	0.659
p.A44E	ACH-002179	Breast Cancer	CCLE	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation altering degron motif	0.659
p.A44E	OCUB-M	breast	COSMIC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation altering degron motif	0.659
p.T41P	ACH-002247	Non-Cancerous	CCLE	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2778
p.T41P	IM-9	haematopoietic and lymphoid tissue	COSMIC	PADVTPEK	DEG_SCF_SKP2-CKS1_1	43:50	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc