DegronMD - Q8IXP5(C11orf53)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P179L	DO231534	LINC	ICGC	PPPY	ITCH	179:182	Mutation altering degron motif	0.7582
p.S134R	TCGA-MH-A560	KIRP	TCGA	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation altering degron motif	0.7427
p.S134R	DO48474	KIRP	ICGC	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation altering degron motif	0.7427
p.T189M	TCGA-B5-A11N	UCEC	TCGA	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.7423
p.T189M	DO41458	UCEC	ICGC	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.7423
p.T189M	SIDM00500	Colorectal Carcinoma	GDSC	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.7423
p.T189M	ACH-000959	Colon/Colorectal Cancer	CCLE	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.7423
p.T133M	TCGA-XK-AAIW	PRAD	TCGA	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation altering degron motif	0.7423
p.T133M	DO51407	PRAD	ICGC	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation altering degron motif	0.7423
p.T133M	SIDM00090	Ovarian Carcinoma	GDSC	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation altering degron motif	0.7423
p.P183S	TCGA-EE-A2M5	SKCM	TCGA	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.6752
p.P183S	DO222423	MELA	ICGC	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.6752
p.P183S	DO37425	SKCM	ICGC	PFTPFMT	DEG_SCF_FBW7_1	183:189	Mutation altering degron motif	0.6752
p.G66E	TCGA-BT-A2LB	BLCA	TCGA	DYR	CBL_MET	67:69	Mutation rewiring degron network	0.3056
p.G66E	DO44098	BLCA	ICGC	DYR	CBL_MET	67:69	Mutation rewiring degron network	0.3056
p.L136I	TCGA-78-8662	LUAD	TCGA	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation rewiring degron network	0.2778
p.L136I	DO45346	LUAD	ICGC	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation rewiring degron network	0.2778
p.T128I	TCGA-AJ-A23O	UCEC	TCGA	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation rewiring degron network	0.2778
p.T128I	TCGA-G4-6302	COAD	TCGA	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation rewiring degron network	0.2778
p.T128I	DO8778	COAD	ICGC	PPSTS	DEG_SPOP_SBC_1	130:134	Mutation rewiring degron network	0.2778

Showing 1 to 20 of 59 entries

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DegronMD: protein-targeted degradation, mutation and drug response to degrons

C11orf53

UniProt ID: Q8IXP5

Entrez ID: 341032

Protein name: Uncharacterized protein C11orf53

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C11orf53 in