DegronMD - Q8IY42(C4orf19)

GO - Biological processes (BP): View more >>

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GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N99S	TCGA-CA-6717	COAD	TCGA	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.2222
p.N99S	DO8264	COAD	ICGC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.2222
p.H94R	TCGA-DD-AAEA	LIHC	TCGA	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.0833
p.H94R	DO52266	LIHC	ICGC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.0833
p.Q108H	TCGA-DX-A6YV	SARC	TCGA	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation altering degron motif	0.647
p.Q108H	DO220011	SARC	ICGC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation altering degron motif	0.647
p.Q117H	DO229019	LICA	ICGC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.1389
p.G97S	SIDM00210	Ovarian Carcinoma	GDSC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.1667
p.G97S	SIDM00094	Kidney Carcinoma	GDSC	PAATPQPT	DEG_SCF_FBW7_1	103:110	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons