DegronMD - Q8IY81(FTSJ3)

FTSJ3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E339D	TCGA-AA-3947	COAD	TCGA	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation rewiring degron network	0.3056
p.E339D	DO8192	COAD	ICGC	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation rewiring degron network	0.3056
p.D340A	TCGA-BH-A18G	BRCA	TCGA	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation rewiring degron network	0.2778
p.D340A	DO3686	BRCA	ICGC	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation rewiring degron network	0.2778
p.E325D	DO229036	LICA	ICGC	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation rewiring degron network	0.1111
p.T348I	SIDM00971	Breast Carcinoma	GDSC	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation blocking phosphorylation signal	0.5
p.T348I	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	SLSSGE	DEG_Kelch_Keap1_1	333:338	Mutation blocking phosphorylation signal	0.5

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*NOTE: the Kaplan plots were collected from OncoLnc