DegronMD - Q8IYS2(KIAA2013)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G222W	TCGA-FS-A1ZC	SKCM	TCGA	AFTST	DEG_SPOP_SBC_1	231:235	Mutation rewiring degron network	0.0833
p.G222W	DO37487	SKCM	ICGC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation rewiring degron network	0.0833
p.P229S	DO222542	MELA	ICGC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation rewiring degron network	0.2778
p.T233S	SIDM00611	Kidney Carcinoma	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005
p.T233S	SIDM00239	Kidney Carcinoma	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005
p.T233S	SIDM00580	Acute Myeloid Leukemia	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005
p.T233S	SIDM00018	Acute Myeloid Leukemia	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005
p.T233S	SIDM01033	Bladder Carcinoma	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005
p.T233S	SIDM01336	Glioblastoma	GDSC	AFTST	DEG_SPOP_SBC_1	231:235	Mutation altering degron motif	0.6005

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons