DegronMD - Q8IZ69(TRMT2A)

TRMT2A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q576H	TCGA-D5-6531	COAD	TCGA	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.647
p.Q576H	DO7983	COAD	ICGC	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.647
p.E587Q	TCGA-ZF-AA51	BLCA	TCGA	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation rewiring degron network	0.1667
p.E587Q	DO219093	BLCA	ICGC	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation rewiring degron network	0.1667
p.A571V	SIDM01617	Endometrial Carcinoma	GDSC	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation rewiring degron network	0.2222
p.P578L	ACH-000955	Colon/Colorectal Cancer	CCLE	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.7582
p.P578L	ACH-002296	Head and Neck Cancer	CCLE	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.7582
p.P578L	PCI-38	upper aerodigestive tract	COSMIC	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.7582
p.P578L	SNU-407	large intestine	COSMIC	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation altering degron motif	0.7582
p.E587G	ACH-000975	Lung Cancer	CCLE	PQTPHCE	DEG_SCF_FBW7_2	575:581	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc