DegronMD - Q8IZY2(ABCA7)

ABCA7

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T80A	TCGA-69-7979	LUAD	TCGA	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation rewiring degron network	0.25
p.T80A	DO23874	LUAD	ICGC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation rewiring degron network	0.25
p.E89D	TCGA-A5-A1OF	UCEC	TCGA	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5647
p.E89D	DO42568	UCEC	ICGC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5647
p.E89D	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5647
p.E89D	ACH-002222	Leukemia	CCLE	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5647
p.E89D	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5647
p.E90K	TCGA-D9-A6EC	SKCM	TCGA	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.7022
p.E90K	DO50291	SKCM	ICGC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.7022
p.L73F	DO222798	COCA	ICGC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation rewiring degron network	0.0556
p.L85M	SIDM00203	Ewing's Sarcoma	GDSC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5999
p.L85M	SIDM01387	Small Cell Lung Carcinoma	GDSC	PQLTPGEE	DEG_SCF_FBW7_2	83:90	Mutation altering degron motif	0.5999

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*NOTE: the Kaplan plots were collected from OncoLnc