DegronMD - Q8N0Z8(PUSL1)

PUSL1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T129A	TCGA-06-5416	GBM	TCGA	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.6028
p.T129A	DO10880	GBM	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.6028
p.R140W	TCGA-2J-AABO	PAAD	TCGA	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1944
p.R140W	DO51666	PAAD	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1944
p.A125T	TCGA-CU-A0YR	BLCA	TCGA	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.2778
p.A125T	DO449	BLCA	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.2778
p.L134M	TCGA-EE-A2GI	SKCM	TCGA	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.5999
p.L134M	DO37410	SKCM	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.5999
p.Y130C	DO230326	COCA	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.5976
p.R133L	DO228974	LICA	ICGC	SRTYLYRLA	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.7316

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*NOTE: the Kaplan plots were collected from OncoLnc