DegronMD - Q8N140(EID3)

EID3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L28P	TCGA-AP-A1DK	UCEC	TCGA	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1111
p.L28P	DO42033	UCEC	ICGC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1111
p.D24Y	TCGA-AP-A1DV	UCEC	TCGA	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.2222
p.D24Y	DO43186	UCEC	ICGC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.2222
p.C12Y	DO233103	GACA	ICGC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.25
p.A10T	DO233748	GACA	ICGC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1944
p.D22N	DO229275	THCA	ICGC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.2778
p.S18F	SIDM00672	Hepatocellular Carcinoma	GDSC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation altering degron motif	0.9093
p.A9P	SIDM00715	Non-Small Cell Lung Carcinoma	GDSC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1667
p.A9P	NCI-H2030	lung	COSMIC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1667
p.L27R	SIDM00930	Osteosarcoma	GDSC	DLSSGE	DEG_Kelch_Keap1_1	15:20	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc