DegronMD - Q8N2I9(STK40)

STK40

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L97M	TCGA-AJ-A5DW	UCEC	TCGA	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation rewiring degron network	0.2222
p.L97M	DO50075	UCEC	ICGC	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation rewiring degron network	0.2222
p.Y94C	TCGA-CK-4951	COAD	TCGA	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation rewiring degron network	0.3056
p.Y94C	DO10582	COAD	ICGC	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation rewiring degron network	0.3056
p.E93K	DO233787	GACA	ICGC	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation altering degron motif	0.7022
p.E93K	DO46346	OV	ICGC	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation altering degron motif	0.7022
p.R89Q	SIDM01619	Endometrial Carcinoma	GDSC	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation altering degron motif	0.7329
p.R84Q	ACH-000984	Endometrial/Uterine Cancer	CCLE	KMLLHTE	LIG_APCC_ABBAyCdc20_2	87:93	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc