DegronMD - Q8N412(STPG2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K75N	TCGA-BS-A0TC	UCEC	TCGA	TRSVDVPSI	DEG_COP1_1	83:91	Mutation substituting flanking lysine	0.2222
p.K75N	DO42400	UCEC	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation substituting flanking lysine	0.2222
p.P92L	TCGA-D3-A8GI	SKCM	TCGA	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.3056
p.P92L	DO50284	SKCM	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.3056
p.P92S	TCGA-LN-A4A8	ESCA	TCGA	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.3056
p.H101Y	TCGA-W3-AA1V	SKCM	TCGA	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.0556
p.H101Y	DO51276	SKCM	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.0556
p.C94F	DO19048	KIRC	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.25
p.R84G	DO52159	PAEN	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation altering degron motif	0.6457
p.G99C	DO229250	THCA	ICGC	TRSVDVPSI	DEG_COP1_1	83:91	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons