DegronMD - Q8N442(GUF1)

GUF1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K435T	TCGA-B5-A11E	UCEC	TCGA	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.2778
p.K435T	DO41644	UCEC	ICGC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.2778
p.P433S	TCGA-DA-A960	SKCM	TCGA	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.2222
p.P433S	DO219482	SKCM	ICGC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.2222
p.T429I	TCGA-IB-7651	PAAD	TCGA	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1111
p.T429I	DO46657	PAAD	ICGC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1111
p.A436S	DO229028	LICA	ICGC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.3056
p.V437L	DO229026	LICA	ICGC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation altering degron motif	0.6765
p.R448K	SIDM01146	Gastric Carcinoma	GDSC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1389
p.R448K	ACH-000932	Gastric Cancer	CCLE	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1389
p.R448K	NCI-SNU-1	stomach	COSMIC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1389
p.E449G	SIDM01173	Rhabdomyosarcoma	GDSC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1111
p.E449G	TE-441-T	soft tissue	COSMIC	VLSSS	DEG_SPOP_SBC_1	437:441	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc