DegronMD - Q8N4L8(CCDC24)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G292V	TCGA-GN-A265	SKCM	TCGA	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.3056
p.G292V	DO37491	SKCM	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.3056
p.A305V	DO229013	COCA	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO229016	COCA	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO229003	COCA	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO229480	LAML	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO229489	LAML	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO230522	LUSC	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305V	DO230539	LUSC	ICGC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.R290S	SIDM01117	Small Cell Lung Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.R290S	SIDM00690	Head and Neck Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.R290S	SIDM01147	Gastric Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.R290S	SIDM00793	Burkitt's Lymphoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.R290S	SIDM01752	Pancreatic Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.R290S	SIDM01525	Acute Myeloid Leukemia	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.25
p.A305T	SIDM00953	Small Cell Lung Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944
p.A305T	SIDM01322	Oral Cavity Carcinoma	GDSC	PASTPMSS	DEG_SCF_FBW7_1	293:300	Mutation rewiring degron network	0.1944

Kaplan plot for CCDC24 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CCDC24

UniProt ID: Q8N4L8

Entrez ID: 149473

Protein name: Coiled-coil domain-containing protein 24

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CCDC24 in