DegronMD - Q8N5B7(CERS5)

CERS5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D348Y	TCGA-78-8660	LUAD	TCGA	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.2222
p.R349H	TCGA-BR-8591	STAD	TCGA	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.25
p.R349C	TCGA-CA-6717	COAD	TCGA	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.25
p.R349C	TCGA-DD-AAD1	LIHC	TCGA	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.25
p.D351N	SIDM01233	Colorectal Carcinoma	GDSC	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.3056
p.D351N	ACH-000003		CCLE	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.3056
p.D351N	ACH-000009	Colon/Colorectal Cancer	CCLE	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.3056
p.D351N	C2BBe1	large intestine	COSMIC	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.3056
p.S345L	SIDM00217	Colorectal Carcinoma	GDSC	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.1389
p.S345L	ACH-000999	Colon/Colorectal Cancer	CCLE	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.1389
p.S345L	SNU-1040	large intestine	COSMIC	VESSS	DEG_SPOP_SBC_1	352:356	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc