DegronMD - Q8N5U0(C11orf42)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P238R	TCGA-50-6590	LUAD	TCGA	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2222
p.P238R	DO24692	LUAD	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2222
p.P228H	TCGA-86-8358	LUAD	TCGA	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.6583
p.P228H	DO25471	LUAD	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.6583
p.N229D	TCGA-A6-6781	COAD	TCGA	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.5821
p.N229D	DO8447	COAD	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.5821
p.V226I	TCGA-AP-A0LQ	UCEC	TCGA	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.5965
p.V226I	DO42625	UCEC	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.5965
p.N224K	TCGA-G5-6233	READ	TCGA	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2778
p.N224K	DO36626	READ	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2778
p.P220S	DO222427	BTCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1667
p.P242S	DO229010	COCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.P242S	DO229013	COCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.P242S	DO229016	COCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.P242S	DO229003	COCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.P242S	DO229005	COCA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.P242S	DO228950	LICA	ICGC	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1111
p.K216E	ACH-000593	Bladder Cancer	CCLE	VRPNLSIMP	DEG_APCC_DBOX_1	226:234	Mutation substituting flanking lysine	0.1667

Kaplan plot for C11orf42 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C11orf42

UniProt ID: Q8N5U0

Entrez ID: 160298

Protein name: Uncharacterized protein C11orf42

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for C11orf42 in