DegronMD - Q8N6C8(LILRA3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G12V	TCGA-97-8172	LUAD	TCGA	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.G12V	DO26384	LUAD	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.D16G	TCGA-EI-6917	READ	TCGA	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.0556
p.D16G	DO36881	READ	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.0556
p.D16G	ACH-000738	Brain Cancer	CCLE	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.0556
p.L11I	TCGA-EO-A22R	UCEC	TCGA	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1944
p.L11I	DO42713	UCEC	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1944
p.G12R	TCGA-YL-A9WK	PRAD	TCGA	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.G12R	DO225216	BRCA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.G12R	DO227480	BRCA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.G12R	DO51443	PRAD	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1667
p.G15V	DO51893	BLCA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.0833
p.T6M	DO224640	BRCA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation altering degron motif	0.7423
p.T6M	DO52538	BRCA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation altering degron motif	0.7423
p.L5F	DO10276	COAD	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation altering degron motif	0.587
p.L5F	DO43041	UCEC	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation altering degron motif	0.587
p.P3S	DO231075	LUSC	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation altering degron motif	0.6752
p.S14N	DO222880	MELA	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.1111
p.S10I	DO42713	UCEC	ICGC	MTPILT	DEG_SCF_FBW7_1	1:6	Mutation rewiring degron network	0.2222

Kaplan plot for LILRA3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

LILRA3

UniProt ID: Q8N6C8

Entrez ID: 11026

Protein name: Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for LILRA3 in