DegronMD - Q8N7E2(CBLL2)

CBLL2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A251V	SIDM00403	T-Lymphoblastic Leukemia	GDSC	PPDY	ITCH	256:259	Mutation rewiring degron network	0.1944
p.A251V	SIDM00049	Colorectal Carcinoma	GDSC	PPDY	ITCH	256:259	Mutation rewiring degron network	0.1944
p.A251V	SIDM01140	Ovarian Carcinoma	GDSC	PPDY	ITCH	256:259	Mutation rewiring degron network	0.1944
p.S308L	SIDM00889	Cervical Carcinoma	GDSC	ALTTT	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.S308L	C-33-A	cervix	COSMIC	ALTTT	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.D258N	SIDM01128	Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	256:259	Mutation altering degron motif	0.5821
p.D258N	NCI-H526	lung	COSMIC	PPDY	ITCH	256:259	Mutation altering degron motif	0.5821
p.Q312P	SIDM01140	Ovarian Carcinoma	GDSC	ALTTT	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc