DegronMD - Q8N7S6(ARIH2OS)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D86N	TCGA-C4-A0F1	BLCA	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.1111
p.D86N	DO581	BLCA	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.1111
p.E104K	TCGA-D3-A1Q5	SKCM	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.E104K	TCGA-ER-A2NC	SKCM	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.E104K	DO37827	SKCM	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.E104K	DO47318	SKCM	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.E104K	ACH-000812	Skin Cancer	CCLE	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.E104K	COLO-783	skin	COSMIC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.P103T	TCGA-EB-A85I	SKCM	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.3056
p.P103T	DO50296	SKCM	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.3056
p.P103Q	TCGA-G7-6797	KIRP	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.3056
p.P103Q	DO20917	KIRP	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.3056
p.A87T	TCGA-ZF-A9R9	BLCA	TCGA	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.1389
p.A87T	DO219066	BLCA	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.1389
p.A92T	DO225209	BRCA	ICGC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation rewiring degron network	0.2778
p.P100S	ACH-000226	Lymphoma	CCLE	SSRRVVPTA	DEG_COP1_1	94:102	Mutation altering degron motif	0.6752
p.P100S	SUP-M2	haematopoietic and lymphoid tissue	COSMIC	SSRRVVPTA	DEG_COP1_1	94:102	Mutation altering degron motif	0.6752
p.P100A	ACH-001818	Bone Cancer	CCLE	SSRRVVPTA	DEG_COP1_1	94:102	Mutation altering degron motif	0.7503

Kaplan plot for ARIH2OS in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ARIH2OS

UniProt ID: Q8N7S6

Entrez ID:

Protein name: Uncharacterized protein ARIH2OS (Ariadne-2 homolog opposite strand protein)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ARIH2OS in