DegronMD - Q8N8Z3(DIP2C-AS1)

DIP2C-AS1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S171G	DO38376	STAD	ICGC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation altering degron motif	0.5882
p.L158F	ACH-000971	Colon/Colorectal Cancer	CCLE	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.1389
p.L158F	HCT-116	large intestine	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.1389
p.P167L	ACH-001318	Liver Cancer	CCLE	TPPALVSPT	DEG_SIAH_1	165:173	Mutation altering degron motif	0.6471
p.P179H	ACH-001613	Leukemia	CCLE	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.1667
p.G183R	MFE-319	endometrium	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.0556
p.G183R	LU-99A	lung	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.0556
p.P161S	AsPC-1	pancreas	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.2222
p.Q155E	LP-1	haematopoietic and lymphoid tissue	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.0556
p.Q155E	Daudi	haematopoietic and lymphoid tissue	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.0556
p.S164N	BT-483	breast	COSMIC	TPPALVSPT	DEG_SIAH_1	165:173	Mutation rewiring degron network	0.3056

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc