DegronMD - Q8N983(MRPL43)

MRPL43

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S178L	DO737	BLCA	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1667
p.S178L	DO51248	SKCM	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1667
p.S198P	DO223732	CESC	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.0556
p.D183N	DO233254	GACA	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.3056
p.M196V	DO48713	LGG	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1111
p.P185H	DO229015	LICA	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.7694
p.P185S	DO48550	SKCM	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.6752
p.Q192R	DO229248	THCA	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.2222
p.T189I	DO41999	UCEC	ICGC	PISSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc