DegronMD - Q8N9N2(ASCC1)

ASCC1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R5H	TCGA-B5-A11E	UCEC	TCGA	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.R5H	TCGA-CM-4743	COAD	TCGA	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.R5H	DO8103	COAD	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.R5H	DO41644	UCEC	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.P20Q	TCGA-D3-A2JC	SKCM	TCGA	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.1111
p.P20Q	DO233864	GACA	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.1111
p.P20Q	DO47578	SKCM	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.1111
p.R10I	DO222884	COCA	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.6991
p.Q22K	DO229015	LICA	ICGC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.0556
p.V3A	SIDM00087	Plasma Cell Myeloma	GDSC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.3056
p.L4V	SIDM00476	Ovarian Carcinoma	GDSC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.5654
p.L4V	ACH-001373	Ovarian Cancer	CCLE	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.5654
p.L4V	OV-17R	ovary	COSMIC	LRPQLIRID	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.5654

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*NOTE: the Kaplan plots were collected from OncoLnc