DegronMD - Q8N9W4(GOLGA6L2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S63L	TCGA-AX-A05Z	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.3056
p.S63L	DO40884	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.3056
p.E64D	TCGA-QN-A5NN	UCS	TCGA	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.2778
p.N54H	DO229016	COCA	ICGC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.2222
p.N54H	DO231233	LAML	ICGC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.2222
p.N54H	DO228952	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.2222
p.T72K	DO229052	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.0556
p.R51Q	NALM-6	haematopoietic and lymphoid tissue	COSMIC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation substituting flanking lysine	0.25
p.R58Q	CL-40	large intestine	COSMIC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation altering degron motif	0.7329
p.R64Q	NCI-H358	lung	COSMIC	PETTT	DEG_SPOP_SBC_1	58:62	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons