DegronMD - Q8N9W5(DNAAF3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L14P	DO220826	BRCA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1389
p.S7C	DO48982	CESC	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7541
p.P4T	DO14662	HNSC	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7031
p.P4T	DO229029	LICA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7031
p.E13G	DO228531	LICA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.S16R	DO228948	LICA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.0833
p.A11E	DO229028	LICA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.2222
p.P8L	DO222775	MELA	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.P8L	DO47665	SKCM	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.P8L	SIDM00189	Melanoma	GDSC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.P8L	CP67-MEL	skin	COSMIC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.L11S	DO48032	STAD	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.2222
p.S10P	DO42673	UCEC	ICGC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.25
p.A11T	SIDM01154	T-Lymphoblastic Leukemia	GDSC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.2222
p.A11T	ACH-000953	Leukemia	CCLE	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.2222
p.A11T	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.2222
p.E13K	SIDM01228	Melanoma	GDSC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.E13K	CHL-1	skin	COSMIC	MTTPAGS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667

Kaplan plot for DNAAF3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DNAAF3

UniProt ID: Q8N9W5

Entrez ID: 352909

Protein name: Dynein axonemal assembly factor 3

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DNAAF3 in