DegronMD - Q8NA47(CCDC63)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G545R	TCGA-17-Z055	LUAD	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1667
p.G545R	SIDM00850	Gastric Carcinoma	GDSC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1667
p.G545R	AGS	stomach	COSMIC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1667
p.R544C	TCGA-19-1787	GBM	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1944
p.P549S	TCGA-44-5644	LUAD	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.0556
p.P549S	DO25153	LUAD	ICGC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.0556
p.E542G	TCGA-A5-A1OF	UCEC	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.25
p.R539Q	TCGA-AA-3845	COAD	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation altering degron motif	0.6218
p.S547G	TCGA-BA-4077	HNSC	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1111
p.S547G	DO15647	HNSC	ICGC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.1111
p.V543M	TCGA-DD-AAVV	LIHC	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.2222
p.D531N	TCGA-EI-6917	READ	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.2222
p.D531N	TCGA-EO-A22R	UCEC	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.2222
p.E542A	TCGA-EO-A3AV	UCEC	TCGA	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.25
p.S540I	DO228976	LICA	ICGC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.3056
p.Y533H	SIDM01608	Endometrial Carcinoma	GDSC	LKENR	DEG_APCC_KENBOX_2	535:539	Mutation rewiring degron network	0.2778

Kaplan plot for CCDC63 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CCDC63

UniProt ID: Q8NA47

Entrez ID: 160762

Protein name: Coiled-coil domain-containing protein 63

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for CCDC63 in