DegronMD - Q8NC42(RNF149)

RNF149

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D86Y	TCGA-DK-A6AW	BLCA	TCGA	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1389
p.D86Y	DO48566	BLCA	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1389
p.R104Q	DO225198	BRCA	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.25
p.A107T	DO228936	LICA	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1667
p.D93N	DO228940	LICA	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation altering degron motif	0.6932
p.P83S	DO229123	NKTL	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.0556
p.W109L	DO220122	SARC	ICGC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1111
p.G85R	SIDM00652	Small Cell Lung Carcinoma	GDSC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1111
p.G85R	ACH-000780	Lung Cancer	CCLE	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1111
p.G85R	NCI-H1105	lung	COSMIC	DTRFFVPEP	DEG_COP1_1	93:101	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc