DegronMD - Q8NC74(RBBP8NL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T593R	TCGA-AF-2689	READ	TCGA	ATTST	DEG_SPOP_SBC_1	591:595	Mutation altering degron motif	0.7876
p.T593R	DO36822	READ	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation altering degron motif	0.7876
p.G599E	TCGA-CC-A9FW	LIHC	TCGA	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2222
p.G599E	DO219557	LIHC	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2222
p.E582K	DO223048	ESCA	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.0833
p.A589E	DO229019	LICA	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2778
p.S586R	DO229036	LICA	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.1944
p.T596N	DO229041	LICA	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.3056
p.S594R	DO229060	LICA	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation altering degron motif	0.7427
p.T593M	DO230918	LUSC	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation altering degron motif	0.7423
p.T593M	DO224546	LUSC	ICGC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation altering degron motif	0.7423
p.G597R	SIDM01163	Non-Small Cell Lung Carcinoma	GDSC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2778
p.G597R	ACH-000677	Lung Cancer	CCLE	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2778
p.G597R	SW1573	lung	COSMIC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.2778
p.T605I	SIDM00516	Melanoma	GDSC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.0556
p.T605I	ACH-002166	Skin Cancer	CCLE	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.0556
p.T605I	MZ7-mel	skin	COSMIC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.0556
p.P600H	SIDM01726	Ewing's Sarcoma	GDSC	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.1944
p.P600H	ACH-000119	Non-Cancerous	CCLE	ATTST	DEG_SPOP_SBC_1	591:595	Mutation rewiring degron network	0.1944

Kaplan plot for RBBP8NL in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RBBP8NL

UniProt ID: Q8NC74

Entrez ID: 140893

Protein name: RBBP8 N-terminal-like protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RBBP8NL in