DegronMD - Q8NCK7(SLC16A11)

SLC16A11

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P453S	TCGA-AX-A2H4	UCEC	TCGA	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.1111
p.P453S	DO41193	UCEC	ICGC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.1111
p.G447R	TCGA-DA-A95V	SKCM	TCGA	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.2778
p.G447R	DO219478	SKCM	ICGC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.2778
p.Q454K	TCGA-ER-A19T	SKCM	TCGA	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0833
p.T441K	DO229025	LICA	ICGC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation altering degron motif	0.7306
p.E445A	SIDM00353	Other Sarcomas	GDSC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation altering degron motif	0.7701
p.E445A	RKN	ovary	COSMIC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation altering degron motif	0.7701
p.A455T	SIDM00013	Melanoma	GDSC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0556
p.A455T	SIDM00710	Small Cell Lung Carcinoma	GDSC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0556
p.A455T	ACH-000394	Lung Cancer	CCLE	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0556
p.A455T	NCI-H2081	lung	COSMIC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0556
p.G429R	NCI-H630	large intestine	COSMIC	PPATPPPE	DEG_SCF_FBW7_2	438:445	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc