DegronMD - Q8NCR3(MFI)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P307H	TCGA-06-5416	GBM	TCGA	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation altering degron motif	0.7694
p.P307H	DO10880	GBM	ICGC	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation altering degron motif	0.7694
p.N295H	TCGA-AG-A002	READ	TCGA	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation rewiring degron network	0.0556
p.N295H	TCGA-EO-A3AY	UCEC	TCGA	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation rewiring degron network	0.0556
p.N295H	DO43202	UCEC	ICGC	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation rewiring degron network	0.0556
p.T306M	TCGA-GV-A6ZA	BLCA	TCGA	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation altering degron motif	0.7423
p.T306M	DO49776	BLCA	ICGC	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation altering degron motif	0.7423
p.T306M	DO229389	BTCA	ICGC	LTPDST	DEG_SCF_FBW7_1	305:310	Mutation altering degron motif	0.7423

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons