DegronMD - Q8NCW0(KREMEN2)

KREMEN2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R50C	TCGA-UF-A7JS	HNSC	TCGA	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.1111
p.R50C	DO52119	HNSC	ICGC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.1111
p.Q65H	DO233262	GACA	ICGC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.3056
p.T66S	DO233262	GACA	ICGC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.2778
p.G55E	SIDM00617	Hepatocellular Carcinoma	GDSC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.25
p.G55E	JHH-2	liver	COSMIC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.25
p.S72N	SIDM00510	Small Cell Lung Carcinoma	GDSC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.1111
p.S72N	Sarc9371	bone	COSMIC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.1111
p.A56S	SIDM00182	Head and Neck Carcinoma	GDSC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.2778
p.A56S	ACH-002265	Head and Neck Cancer	CCLE	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.2778
p.A56S	LB771-HNC	upper aerodigestive tract	COSMIC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation rewiring degron network	0.2778
p.F62L	SIDM01691	Chronic Myelogenous Leukemia	GDSC	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation altering degron motif	0.6981
p.F62L	ACH-000321	Leukemia	CCLE	RPCLFWD	LIG_APCC_ABBAyCdc20_2	58:64	Mutation altering degron motif	0.6981

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*NOTE: the Kaplan plots were collected from OncoLnc