DegronMD - Q8NE62(CHDH)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M518T	TCGA-AX-A0J0	UCEC	TCGA	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.1944
p.M518T	DO41133	UCEC	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.1944
p.E538K	TCGA-GN-A266	SKCM	TCGA	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.1389
p.E538K	DO37432	SKCM	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.1389
p.V528A	DO233179	GACA	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation altering degron motif	0.6936
p.P524H	DO229037	LICA	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation altering degron motif	0.7694
p.V537L	DO221123	MALY	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.1667
p.P521S	DO229494	SKCA	ICGC	DPTAVVDPQ	DEG_SIAH_1	523:531	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons