DegronMD - Q8NET8(TRPV3)

TRPV3

UniProt ID: Q8NET8

Entrez ID: 162514

Protein name: Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A41T	TCGA-2W-A8YY	CESC	TCGA	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.25
p.A41T	DO223732	CESC	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.25
p.P31Q	TCGA-95-7043	LUAD	TCGA	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.5924
p.P31Q	DO24739	LUAD	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.5924
p.P31L	TCGA-AA-3877	COAD	TCGA	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6471
p.P31L	DO7855	COAD	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6471
p.P31L	SIDM01176	B-Lymphoblastic Leukemia	GDSC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6471
p.P31L	ACH-000059	Leukemia	CCLE	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6471
p.P31L	SUP-B15	haematopoietic and lymphoid tissue	COSMIC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6471
p.E46Q	TCGA-EI-6506	READ	TCGA	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1111
p.E46Q	DO36780	READ	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1111
p.S40I	TCGA-EO-A22U	UCEC	TCGA	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.2778
p.S40I	DO43755	UCEC	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.2778
p.I25V	DO229010	COCA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1667
p.I25V	DO229013	COCA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1667
p.I25V	DO229016	COCA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1667
p.I25V	DO229003	COCA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1667
p.I25V	DO229005	COCA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1667
p.P36L	DO50970	LICA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.7582
p.E46K	DO222420	MELA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation rewiring degron network	0.1111
p.P31R	DO232861	NACA	ICGC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.6401
p.P31T	SIDM00068	Colorectal Carcinoma	GDSC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.5919
p.P31T	ACH-002394	Colon/Colorectal Cancer	CCLE	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.5919
p.P31T	GEO	large intestine	COSMIC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.5919
p.P38L	HCT-15	large intestine	COSMIC	PAEITPTK	DEG_SCF_SKP2-CKS1_1	31:38	Mutation altering degron motif	0.7582

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*NOTE: the Kaplan plots were collected from OncoLnc