DegronMD - Q8NFB2(TMEM185A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T331A	DO52370	LUSC	ICGC	IAPMFRKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation blocking phosphorylation signal	0.75
p.R323Q	SIDM01942	Colorectal Carcinoma	GDSC	IAPMFRKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation altering degron motif	0.6218
p.G335R	SIDM00007	Other Solid Cancers	GDSC	IAPMFRKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation rewiring degron network	0.1944
p.I318F	SIDM00541	Colorectal Carcinoma	GDSC	IAPMFRKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation altering degron motif	0.7415

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons