DegronMD - Q8NFP4(MDGA1)

MDGA1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V478M	TCGA-D3-A51G	SKCM	TCGA	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.1111
p.V478M	DO47700	SKCM	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.1111
p.V473E	TCGA-DM-A1HB	COAD	TCGA	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.25
p.R466W	DO220484	KICH	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation altering degron motif	0.8634
p.R454S	DO229041	LICA	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.1389
p.L461M	DO229008	LICA	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation altering degron motif	0.711
p.T452I	DO38731	STAD	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.0833
p.L474R	DO229264	THCA	ICGC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation rewiring degron network	0.2222
p.C463R	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation altering degron motif	0.719
p.L461P	SIDM01617	Endometrial Carcinoma	GDSC	LQCEVRGKPR	SCF_FBXL2	461:470	Mutation altering degron motif	0.7582

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*NOTE: the Kaplan plots were collected from OncoLnc