DegronMD - Q8NFU4(FDCSP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P73L	TCGA-5N-A9KI	BLCA	TCGA	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.2222
p.P73L	DO223513	BLCA	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.2222
p.E84K	TCGA-AM-5821	COAD	TCGA	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.3056
p.E84K	DO8240	COAD	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.3056
p.E84K	DO218547	GACA	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.3056
p.P71L	TCGA-CR-7368	HNSC	TCGA	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1667
p.P71L	DO14167	HNSC	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1667
p.E74K	TCGA-DF-A2KU	UCEC	TCGA	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.25
p.E74K	DO223286	UCEC	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.25
p.K85N	DO228985	LICA	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.2778
p.P69A	DO222355	LICA	ICGC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1111
p.P69S	SIDM00336	Melanoma	GDSC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1111
p.P69S	ACH-000881	Skin Cancer	CCLE	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1111
p.P69S	MEL-JUSO	skin	COSMIC	PTTPLPS	DEG_SCF_FBW7_1	77:83	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons