DegronMD - Q8NFU5(IPMK)

IPMK

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P35L	TCGA-AJ-A3EK	UCEC	TCGA	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.25
p.P35L	DO41584	UCEC	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.25
p.E18D	TCGA-AJ-A3EL	UCEC	TCGA	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1389
p.E18D	DO41542	UCEC	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1389
p.R41H	DO48442	BLCA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0833
p.T28I	DO228803	GACA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.8189
p.T32N	DO228948	LICA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.7055
p.P23Q	DO229025	LICA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.2778
p.P33Q	DO229027	LICA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.3056
p.P33Q	DO229035	LICA	ICGC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.3056
p.T28A	SIDM01397	Melanoma	GDSC	IESTPEGT	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.825

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*NOTE: the Kaplan plots were collected from OncoLnc