DegronMD - Q8NHG7(SVIP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A29S	TCGA-85-8276	LUSC	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.0556
p.A29S	DO26436	LUSC	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.0556
p.A28D	TCGA-A5-A1OF	UCEC	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.0833
p.A28D	DO42568	UCEC	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.0833
p.R22I	TCGA-AP-A051	UCEC	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.25
p.R22I	DO42673	UCEC	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.25
p.P6H	TCGA-D3-A1QA	SKCM	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.1389
p.P6H	DO47469	SKCM	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.1389
p.P14H	TCGA-DD-AAVV	LIHC	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation altering degron motif	0.6583
p.P14H	DO223912	LIHC	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation altering degron motif	0.6583
p.G9W	TCGA-EM-A2CL	THCA	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.2222
p.G9W	DO40640	THCA	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.2222
p.K21N	TCGA-FZ-5919	PAAD	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.2778
p.K21N	DO218972	PAAD	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.2778
p.A26V	TCGA-XK-AAIW	PRAD	TCGA	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.1389
p.A26V	DO51407	PRAD	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.1389
p.A29E	DO230463	PACA	ICGC	PPTPDLE	DEG_SCF_FBW7_2	13:19	Mutation rewiring degron network	0.0556

Kaplan plot for SVIP in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SVIP

UniProt ID: Q8NHG7

Entrez ID: 258010

Protein name: Small VCP/p97-interacting protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SVIP in