DegronMD - Q8NHW3(MAFA)

MAFA

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F41Y	TCGA-DD-AACT	LIHC	TCGA	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation rewiring degron network	0.0833
p.F41Y	DO219563	LIHC	ICGC	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation rewiring degron network	0.0833
p.S56N	DO233693	GACA	ICGC	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation altering degron motif	0.5958
p.S52L	DO229229	THCA	ICGC	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation altering degron motif	0.6556
p.P66S	SIDM00120	Prostate Carcinoma	GDSC	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation rewiring degron network	0.0833
p.P66S	ACH-000979	Prostate Cancer	CCLE	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation rewiring degron network	0.0833
p.P54S	SIDM01175	Other Sarcomas	GDSC	LSSTPLST	DEG_SCF_FBW7_1	50:57	Mutation altering degron motif	0.6752

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc