DegronMD - Q8TB05(UBALD1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A128T	TCGA-CK-5916	COAD	TCGA	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.0556
p.P74L	DO233210	GACA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1667
p.R71H	DO233766	GACA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.25
p.P74Q	DO228986	LICA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1667
p.P60T	DO229031	LICA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.3056
p.T54K	DO229038	LICA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1389
p.P126L	DO46424	OV	ICGC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1111
p.T64P	DO229204	THCA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation altering degron motif	0.7031
p.T64P	DO229088	THCA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation altering degron motif	0.7031
p.T64P	DO229092	THCA	ICGC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation altering degron motif	0.7031
p.T126M	SIDM00373	Endometrial Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1111
p.S55T	SIDM00305	Ovarian Carcinoma	GDSC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1667
p.S55T	ACH-000132	Ovarian Cancer	CCLE	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1667
p.P73S	ACH-000884	Skin Cancer	CCLE	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation rewiring degron network	0.1944
p.P107A	H2731	pleura	COSMIC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1389
p.A127D	RT-112	urinary tract	COSMIC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.0833
p.E106K	HO-1-u-1	upper aerodigestive tract	COSMIC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1111
p.V66G	LB996-RCC	kidney	COSMIC	MMCTPANT	DEG_SCF_FBW7_1	61:68	Mutation altering degron motif	0.7532
p.P115L	MFE-319	endometrium	COSMIC	AATSS	DEG_SPOP_SBC_1	114:118	Mutation altering degron motif	0.7582

DegronMD: protein-targeted degradation, mutation and drug response to degrons

UBALD1

UniProt ID: Q8TB05

Entrez ID: 124402

Protein name: UBA-like domain-containing protein 1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for UBALD1 in